What Does It Really Mean to Age Well? A few days ago, a video appeared in my TikTok feed featuring Bryan Johnson, the technology entrepreneur who has become famous for his efforts to reverse biological aging. Johnson was discussing how some measurements of his cardiovascular and respiratory fitness resemble those of an 18-year-old. My immediate thought was: What about his joints?

Orthobiologics continues to evolve at the intersection of biology, biomechanics, technology, and clinical judgment. This week’s five stories range from a question I never expected TikTok to make me investigate, whether what we eat could affect our own PRP, to long term intraosseous BMC data in ankle osteoarthritis, tendon health, robotic blood draws, and the increasingly important question of when medical testing is thoughtful medicine rather than “too much.”

ORTHOBIOLOGICS DIGEST™ September 28, 2026 | No. 4 Research. Evidence. Perspective. Curated and interpreted by Deborah Westergaard, M.D. Orthobiologics Digest™ brings together research and news about regenerative medicine, joint and spine preservation, and musculoskeletal health. I explain what the evidence shows, where its limits remain, and how I think about it as a physician in practice since 1989 with experience in anesthesiology and image-guided procedures. This issue con